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"They try to establish a reasonable date to allow for time in the supply chain and pharmacy shelves," he says.
The chemicals in drugs do break down and change over time, becoming more potent (or poisonous) or ineffective.
This page and associated sub-pages allows a user to run an American produced utilitarian bottle or a significantly sized bottle fragment through a series of questions based primarily on diagnostic physical, manufacturing related characteristics or features to determine the approximate manufacturing age range of the item.
Shelf life depends on the degradation mechanism of the specific product.Alan Goldhammer, Ph D, associate vice president for regulatory affairs of the Pharmaceutical Research and Manufacturers of America (Ph RMA), tells Web MD that safety, purity, and potency must be tested and established over time by drug manufacturers.If a drug says the expiration date is 18 months hence, it means these three qualities can only be guaranteed that long, assuming the drug is stored properly.The information on this website will, however, usually produce a reliable manufacturing date range for a majority of American utilitarian bottles manufactured from the early 1800s to the mid-20th century.Using physical, manufacturing related diagnostic features, most utilitarian bottles can usually only be accurately placed within a date range of 10-15 years (i.e., 1870-1880 or 1885) . Like many industries making the leap from manual craftsman production to industrialization and automation, technological advances in bottle manufacturing were not immediately accepted by glass manufacturers or their workers.